https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Comparing differences and similarities between Chinese and American women's experiences of stress urinary incontinence and health-seeking behaviors during pregnancy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38850 n = 178) and the United States of America (n = 178) who experienced SUI using the Impact of Incontinence Questionnaire short form (IIQ-SF). Results: While more Chinese women experienced SUI (p =.049), American women who experienced SUI experienced it earlier in their pregnancy (p =.003) and more frequently (p <.0001) than the Chinese women. Therefore, it can be assumed that although less American women experienced SUI, the impact was greater on their daily living activities. Irrespective of ethnicity, only 14% (n = 18) of women who described having SUI sought medical aid. Conclusion: The disconnect between high incidence and low rates of seeking treatment needs future exploration to develop interventions tailored to educate women about SUI and its role during pregnancy.]]> Wed 16 Feb 2022 14:46:28 AEDT ]]> Modulation of progesterone receptor isoform expression in pregnant human myometrium https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30926 PR isoform expression ex situ and, further, to determine if conditions approaching the in vivo environment stabilise PR isoform expression in culture. Methods: Term nonlaboring human myometrial tissues were cultured under specific conditions: serum supplementation, steroids, stretch, cAMP, PMA, PGF2α, NF-κB inhibitors, or TSA. Following 48 h culture, PR-T, PR-A, and PR-B mRNA levels were determined using qRT-PCR. PR-A/PR-B ratios were calculated. Results: PR-T and PR-A expression and the PR-A/PR-B ratio significantly increased in culture. Steroids prevented the culture-induced increase in PR-T and PR-A expression. Stretch blocked the effects of steroids on PR-T and PR-A expression. PMA further increased the PR-A/PR-B ratio, while TSA blocked culture-induced increases of PR-A expression and the PR-A/PR-B ratio. Conclusion: Human myometrial tissue in culture undergoes changes in PR gene expression consistent with transition toward a laboring phenotype. TSA maintained the nonlaboring PR isoform expression pattern. This suggests that preserving histone and/or nonhistone protein acetylation is critical for maintaining the progesterone dependent quiescent phenotype of human myometrium in culture.]]> Wed 11 Apr 2018 14:38:10 AEST ]]> Saudi Women's knowledge and awareness of the risk of venous thromboembolism during pregnancy and the puerperium and the practice of ‘lying-in’: a mixed methods study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54086 Wed 06 Mar 2024 14:08:46 AEDT ]]> Ngaa-bi-nya-nhumi-nya (to Test First): Piloting the Feasibility of Using the Growth and Empowerment Measure with Aboriginal Pregnant Women Who Smoke https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45304 Thu 27 Oct 2022 09:40:15 AEDT ]]> Predictors of alcohol use during pregnancy in Australian women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44743 Mon 24 Oct 2022 08:35:57 AEDT ]]>